|
Link to this page
Your search term(s) "polycystic kidney disease" returned 35 results.
Displaying all search results.
Children and ADPKD: It's Not Just an Adult Disease. PKD Progress. 23(2): 18. Summer 2007.
This brief article presents an excerpt from the recently updated Polycystic Kidney Disease (PKD) Patient's Manual: Understanding and Living with Autosomal Dominant Polycystic Kidney Disease (ADPKD), a publication available free of charge from the PKD Foundation at www.pkdcure.org. This article reminds readers that children can have autosomal dominant PKD, and that these children tend to fall into two groups: those who are diagnosed before birth or in the first year of life with large kidneys or cysts, and those who are diagnosed after the age of 1 year. The number of cysts a child has affects his or her signs and symptoms. Almost all children who are diagnosed after the first year of life have perfectly normal kidney function that seems to stay normal throughout childhood. Most of these children will maintain normal kidney function until they are into their mid-20s. The article also considers whether or not children should be told they are at risk of ADPKD, whether children of parents with ADPKD should be tested for the disease, and recommendations for routine screening. Sidebars review the characteristics of ADPKD in children.
Full Record Printer Friendly Version
Dialysis and PKD Patients: An Analysis. Nephrology News & Issues. 21(9): 36, 37. August 2007.
This article focuses on the treatment of patients with polycystic kidney disease (PKD) before the need for renal replacement therapy and during chronic dialysis. The authors discuss the complications of PKD, including renal pain, hematuria, and renal infection; the extrarenal manifestations of PKD, including gastrointestinal involvement, hepatic synthetic dysfunction, cardiac valve abnormalities, hypertension, and brain aneurysms in patients with a strong family or personal history of same; the use of heparin in these patients; the use of dietary sodium restriction, diuretics, and antihypertensive medications used to control volume and blood pressure; the role of remaining kidney function, even in patients who require dialysis to maintain health; patient candidacy for dialysis; the decision between home dialysis versus in-center care; the choice between hemodialysis and peritoneal dialysis; and the importance of adequate nutrition to decrease hospitalizations, improve survival, increase independence, and improve sense of well-being. The authors note that PKD patients are generally good candidates for survival and have a survival advantage compared with patients with end-stage renal disease (ESRD) from other causes.
Full Record Printer Friendly Version
Eating Healthy From the Start: Kid and Kidney-Friendly Nutrition Tips. PKD Progress. 23(2): 10-11. Summer 2007.
It is likely that eating well in childhood may offer some protection to the kidneys and influence the early progression of polycystic kidney disease (PKD) in children at risk for the condition. This article offers kid-friendly and kidney-friendly nutrition tips for parents of children who have healthy kidney function whether or not they have been diagnosed with PKD. Specific food and nutrition items discussed include flaxseeds, sodium, fruits and vegetables, protein intake, and soy-based foods. Suggestions for increasing a child's sense of adventure and willingness to try new foods are also provided and focus on families eating meals together, the need to offer new foods on at least 10 different occasions, letting children serve themselves, and including children in shopping and cooking activities. One sidebar reviews how much protein is recommended for children in different age groups—the recommended Dietary Reference Intake for children.
Full Record Printer Friendly Version
Exercise and PKD. PKD Progress. 23(3): 12-13. Fall 2007.
This article reviews the importance of exercise for people who have polycystic kidney disease (PKD). The author interviews Dr. Richard M. Fine, a fitness trainer, who emphasizes that for most people, the ability to exercise is more about overcoming a mental barrier than a physical one. Dr. Fine reviews the steps that can help a patient implement and maintain an exercise plan, including exercising with other people, learning about the emotional benefits of exercise, and incorporating movement and exercise into all one’s daily activities. Two charts summarize a group of exercises for everyone and a group of exercises for people with specific disorders, including diabetes, hypertension, coronary heart disease, and osteoporosis. The charts list the modes of exercise; goals; recommended intensity, frequency, and duration; and expected time to see results.
Full Record Printer Friendly Version
Getting Back on the Wagon and Rid of the Saddle. PKD Progress. 23(1): 16-17. Spring 2007.
This brief article offers a list of 25 ideas for health improvement for people who are in the early stages of polycystic kidney disease (PKD). Designed to capture the attention of people who are making New Year's resolutions, the article suggests that readers enlist the help of friends, trim fat from their diet, eat smaller portions, include more fiber in their diet, learn new recipes or take a cooking class, plan ahead, bring healthy food when traveling or visiting, limit liquid calories, add more movement to the day, try soy foods, include treats that are not food-based, learn about herbs and spices, eat fish, focus on reducing sodium, exercise to fight stress or fatigue, limit artificial sweeteners, use a smaller size plate, do not eat while distracted by television or reading, do not have high fat snack foods in the house, chew food thoroughly, keep a diet diary, wait 20 minutes before taking a second helping of food, avoid fried foods, eat soup, and try to prevent getting over hungry. For each item, the authors offer one or two sentences of explanation and encouragement.
Full Record Printer Friendly Version
Polycystic Kidney Disease. Bethesda, MD: National Kidney and Urologic Diseases Information Clearinghouse. 2007. 7 p.
Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. This fact sheet reviews PKD, focusing on two major inherited forms of PKD and a noninherited form: autosomal dominant PKD, autosomal recessive PKD, and acquired cystic kidney disease (ACKD). Written in a question-and-answer format, the fact sheet covers the definition of each type, symptoms, diagnostic tests used to confirm the condition, and treatment options. The symptoms and signs of PKD include pain in the back and lower sides, headaches, urinary tract infections (UTIs), blood in the urine, and cysts in the kidneys and other organs. Diagnosis of PKD is accomplished by ultrasound imaging of kidney cysts, the ultrasound imaging of cysts in other organs, and family medical testing, including genetic testing. Although there is no cure for PKD, treatments include medicine and surgery to reduce pain, antibiotics to resolve infections, dialysis to replace functions of failed kidneys, and transplantation. The fact sheet concludes with a summary of research programs in this area, a list of resource organizations for readers wanting additional information, and a brief description of the activities of the National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC). 2 figures.
Full Record Printer Friendly Version
Renal Transplantation for ADPKD Patients: A 2007 Update. Nephrology News & Issues. 21(4): 24-27. March 2007.
This article updates readers on the recommendations and advances in the field of kidney transplantation for people with autosomal dominant polycystic kidney disease (ADPKD). The author first considers the benefits of transplantation over other treatments for ADPKD, noting that even when adjusted for diabetes and concomitant heart disease, the transplant patient has a greater life expectancy despite the risks of surgery and the perioperative period. Patients with ADPKD have as good or better outcomes than patients with other kinds of kidney failure. The author also considers the issue of whether to remove the native kidneys as part of a kidney transplant in this patient population. The absolute indications for removal of native polycystic kidneys prior to transplantation are active kidney infections, kidney malignancy, or kidneys that are so large that they mechanically preclude transplantation into the recipient's pelvis. The article also covers family donors in families with ADPKD, costs, living versus cadaveric donation, the kidney allocation process, and immunosuppressive medications.
Full Record Printer Friendly Version
Talking to Your Kids About PKD: A Mommy's Perspective. PKD Progress. 23(2): 13. Summer 2007.
In this brief article, the author shares her experience helping her young son understand why her kidney disease requires her to have special medical care. Diagnosed with polycystic kidney disease (PKD) when the boy was 4 years old, the author reports that the child became troubled and anxious when he suddenly had to go to a babysitter while his mother had weekly doctor appointments. The author describes how she explained the disease and kidney function to the child, and how the approach of providing a lot of information about what is going on has helped to calm him and help him feel more secure. The author concludes by considering the kinds of information she will need to share with her son when she gets ready to have a kidney transplant. 1 figure.
Full Record Printer Friendly Version
Vasopressin Receptor Antagonists. Dialysis and Transplantation. 36(5): 266-74. May 2007.
This article brings readers up-to-date on advances in vasopressin receptor antagonists, drugs that are used to reduce urine osmolality and increase free water excretion while preserving sodium and raising serum sodium concentration. These drugs offer an improvement over traditional diuretics, which increase sodium excretion along with water excretion. The authors first review vasopressin physiology and vasopressin receptors, then discuss specific vasopressin receptor antagonists, including conivaptan, lixivaptan, tolvaptan, and satavaptan. Conivaptan is approved for the treatment of euvolemic hyponatremia, and more trials are needed to investigate its role in the management of acutely decompensated and chronic congestive heart failure (CHF). Tolvaptan may benefit patients with polycystic kidney disease. The authors conclude that vasopressin receptor antagonists are likely to become a key treatment in hospitalized patients who need diuretics. 5 tables. 23 references.
Full Record Printer Friendly Version
Ways You Can Help Promote PKD During National Kidney Month. PKD Progress. 23(1): 4-5. Spring 2007.
This brief article offers a list of 25 ideas to help promote polycystic kidney disease (PKD) awareness during National Kidney Month, which takes place in March of each year. The ideas include hanging up promotional posters; passing along informational packets to health care providers; speaking to community groups and friends about PKD; adding references to PKD to email signatures, websites, and voice mail; contacting local newspapers, television, and radio stations about airing public service announcements; sending bookmarks to local schools; planning chapter events; wearing PKD merchandise; forming a Walk for PKD team; and attending the PKD National Convention. The article describes some promotional materials that are available through the Polycystic Kidney Disease Foundation at pkdcure@pkdcure.org or 800-PKD-CURE.
Full Record Printer Friendly Version
Childhood Kidney Disease Gene Identified. Nephrology News & Issues. 20(3): 16. March 2006.
This brief article reports on the recent identification of a new gene linked to the inherited kidney disorder called Meckel-Gruber syndrome (MKS). Children with MKS have central nervous system deformities as well as abnormal cysts in their kidneys, and usually die shortly after birth. The news of the gene identification is important to MKS families who might have their blood screened for the defect and seek genetic counseling. The finding also is important for better understanding of common birth defects, such as neural tube abnormalities, and for related disorders, such as more common forms of polycystic kidney disease (PKD). The author notes that the current work is an extension of Mayo Clinic researchers' work for more than a decade that has helped to reveal the genetic basis of PKD and to develop therapies. The author briefly reports on the research study methodology and the investigators from different institutions who were part of the research team.
Full Record Printer Friendly Version
Cystic Diseases of the Kidney. IN: Kellogg Parsons, J.; James Wright, E., eds. Brady Urology Manual. New York, NY: Informa Healthcare USA. 2006. pp 107-114.
This chapter about cystic diseases of the kidney is from a reference handbook that offers a comprehensive overview of urology, presented in outline and bulleted formats for ease of access in the busy health care world of hospital emergency rooms and outpatient clinics. The author notes that simple renal cyst is a common, benign condition that is usually detected incidentally. The chapter covers general information, presentation, diagnosis, and treatment of simple renal cyst, acquired renal cystic disease, autosomal dominant polycystic kidney disease (ADPKD), and autosomal recessive polycystic kidney disease (ARPKD). The Bosniak classification system is recommended to distinguish simple cysts from complex renal cysts and cystic renal cell carcinoma (RCC). Acquired renal cystic disease occurs in patients with kidney failure and is characterized by bilateral cortical and/or medullary cysts. ADPKD is an inherited disease of the collecting duct characterized by multiple large renal cysts, progressive renal insufficiency, and extrarenal manifestations, including hepatic cysts and cerebral artery aneurysm. Treatment for ADPKD and ARPKD is supportive care. The chapter concludes with a list of references for additional reading. 19 references.
Full Record Printer Friendly Version
Development and Function of the Pancreas, Bile Duct, and Gallbladder. IN: Ginsberg, G.; Ahmad, N.; Lichtenstein, G., eds. The Clinician’s Guide to Pancreaticobiliary Disorders. Thorofare, NJ: Slack Incorporated. 2006. pp 1-20.
This introductory chapter is from a comprehensive text that covers the epidemiology, pathophysiology, diagnosis, and management of disorders of the pancreatic and biliary systems. The authors of this chapter review the development and function of the pancreas, bile duct, and gallbladder. Specific topics include embryonic development; congenital abnormalities of the pancreas, including pancreas divisum, annular pancreas, heterotopic pancreas, and pancreatic agenesis, hypoplasia, and dysplasia; congenital abnormalities of the intrahepatic biliary ducts, including cystic disorders, autosomal recessive polycystic kidney disease or congenital hepatic fibrosis, Caroli’s syndrome, syndromic-Alagille syndrome, and nonsyndromic bile duct paucity; congenital abnormalities of the extrahepatic biliary ducts, including extrahepatic biliary atresia and choledochal cysts; congenital abnormalities of the gallbladder, including agenesis of the gallbladder, structural variations of the gallbladder, and heterotopic tissue in the gallbladder. For each condition, the authors provide a definition, a description of clinical manifestations and evaluation, and management approaches. The chapter is illustrated with black-and-white photographs. 11 figures. 3 tables. 15 references.
Full Record Printer Friendly Version
Diagnosing PKD, Determining Options. Nephrology News & Issues. 20(3): 62-65. March 2006.
This article provides information about the diagnosis of polycystic kidney disease (PKD). Symptoms lead to the diagnosis of PKD in approximately 34 percent of queried patients. The second most common theme that led to the diagnosis of PKD was a known family history. Almost 32 percent of PKD patients were diagnosed during evaluation of hypertension or asymptomatic microscopic hematuria (blood in the urine). The author outlines the typical types of pain experienced by patients with PKD, describes the diagnostic tests that are used to confirm PKD, and offers suggestions for dealing with patients (particularly regarding health insurance issues and treatment options that may delay or halt the progression of the disease). For example, aggressive and early treatment of hypertension conveys the promise of slowing the progression of the disease. In addition, addressing abnormalities of mineral metabolism, anemia, and dyslipidemia can forestall serious problems. 13 references.
Full Record Printer Friendly Version
Eating for Optimal Health. PKD Progress. 21(2): 12-13, 24. Summer 2006.
This article reviews the use of dietary modifications to help slow the progression of polycystic kidney disease (PKD). Written primarily for newly-diagnosed patients with PKD who are not yet on dialysis, the article discusses lifestyle and dietary tips that are recommended to help patients stay as healthy as possible. These tips are: reduce stress, avoid inflammation in the kidney, use plant-based proteins that are high in antioxidants, incorporate soybeans in the diet, choose low-sodium foods and condiments, limit caffeine and alcohol, increase potassium consumption, include omega-3 fatty acids in the diet, consume high-fiber carbohydrates, maintain an optimal weight, and limit dietary fat intake. The author reminds readers that all of these recommendations are useful to improve anyone’s health, not just the family member with PKD. Readers are also encouraged to start slowly and to incorporate changes into their overall program of nutrition and health.
Full Record Printer Friendly Version
Family and ADPKD: A Guide for Children and Parents. Kansas City, MO: Polycystic Kidney Disease Foundation. 2006. 18 p.
This document provides basic information for the parents of a child that has just been diagnosed with autosomal dominant polycystic kidney disease (ADPKD), a genetic disease that affects the kidneys and other parts of the body. In ADPKD, cysts can form in the kidney, anywhere along the nephron. This fact sheet answers common questions in the areas of general information, inheritance, diagnosis, health promotion, prognosis, extra-renal manifestations, psychosocial factors, and current research on PKD. Specific topics include the anatomy and function of the kidneys, how PKD can damage the good parts of the kidney, diagnosis in people who have no symptoms, dietary approaches to preventing disease progression, limiting protein intake, avoiding dehydration, sodium, sports and recreation, medications, high blood pressure, mortality due to ADPKD, dialysis and kidney transplantation, organ donation, disclosing health information to a child, screening in siblings, complications in ADPKD, cerebral aneurysms, coping with pain, and finding information resources. The information is presented in a kid-friendly fashion, so an adolescent would be comfortable reading the fact sheet by him or herself.
Full Record Printer Friendly Version
Just Diagnosed with Polycystic Kidney Disease (PKD). PKD Progress. 21(2): 6-9. Summer 2006.
This newsletter article helps readers newly diagnosed with polycystic kidney disease (PKD) understand the condition and how they can take an active part in their own health care. The author uses the story of one woman’s experiences with diagnosis, educating herself, and treatment, to help readers understand the process of coping with the disease. PKD is a common, life-threatening, genetic kidney disease that causes cysts to grow, usually on both kidneys. Eventually, the cysts multiply, usually leading to kidney failure, for which transplantation or dialysis are the only treatments. The author reviews symptoms and diagnosis, the tests used to confirm PKD, and possible problems getting health insurance coverage. The author emphasizes the importance of patients getting appropriate medical care for PKD and the complications it may cause (notably hypertension, abnormalities of mineral metabolism, anemia, and dyslipidemia). Readers are encouraged to contact their local chapter of the PKD Foundation. The article concludes with a list of 10 web sites for additional information.
Full Record Printer Friendly Version
Making an Earlier Diagnosis of ADPKD: Implications for the Treatment of Hypertension. Nephrology News & Issues. 20(7): 32-36. June 2006.
This article discusses the problem of hypertension in patients with autosomal dominant polycystic kidney disease (ADPKD). The authors review the incidence and prevalence of hypertension in ADPKD, which usually develops in the second or third decade of life, even before the loss of significant kidney function. Hypertension is associated with increased kidney size, a faster decline in kidney function, left ventricular hypertrophy, premature cardiovascular disease, and mortality. The authors make a case for the earlier diagnosis of ADPKD, in part to start anti-hypertensive therapy earlier and to ensure the correct anti-hypertensive agent is chosen. The authors conclude by recommending screening for at-risk and already-diagnosed adolescents and young adults for hypertension at least annually. Early detection and aggressive treatment can reduce the future likelihood of cardiac and renal injury. 2 figures. 19 references.
Full Record Printer Friendly Version
PKD Patient's Manual: Understanding and Living with Autosomal Dominant Polycystic Kidney Disease. Kansas City, MO: Polycystic Kidney Disease Foundation. 2006. 33 p.
This booklet provides information about autosomal dominant polycystic kidney disease (ADPKD) to those who have the disease, those who are at risk due to an affected family member, and people who care about someone who has been diagnosed with ADPKD. The primary manifestation of ADPKD is cysts in the kidney, cysts as well as other abnormalities can occur in other areas of the body. Written in a question-and-answer format, this booklet covers the epidemiology of ADPKD, symptoms, genetics and inheritance, the ADPKD genes, screening tests for ADPKD, kidney anatomy and function, cysts and their impact on the kidney, high blood pressure (hypertension), weight loss, exercise, sodium, potassium, tobacco use, acute and chronic pain in ADPKD, blood in the urine, urinary tract infection (UTI), kidney stones, liver cysts, dialysis and transplantation, mitral valve prolapse, intracranial aneurysms, hernias, diverticula, pregnancy, diet therapy, fluids, caffeine, children with ADPKD, symptoms of kidney failure, and common tests that are done to diagnose and monitor cystic disease. The booklet concludes with a list of resource organizations through which readers can get more information. 12 figures. 1 table. 2 references.
Full Record Printer Friendly Version
Q & A on PKD [Polycystic Kidney Disease]. Kansas City, MO: Polycystic Kidney Disease Foundation. 2006. 47 p.
This patient education packet covers a wide variety of information about polycystic kidney disease (PKD). The first article brings readers up-to-date on autosomal dominant PKD (ADPKD) genes and proteins; the second section reviews strategies that can be used to treat hypertension and end-organ damage in patients with ADPKD. The remainder of the fact sheet answers questions that patients may have in the areas of diagnosis and genetics, extra-renal manifestations, renal manifestations, pregnancy and birth control, menopause, kidney failure, dialysis and transplantation, diet and drug therapy, surgery, the role of exercise, and pain management. Specific topics covered include multicystic kidneys, multicystic versus polycystic kidney, natural course of the disease in families, spontaneous onset of ADPKD, diagnostic criteria, fetal testing for PKD, medullary sponge kidney, symptom-free PKD, race and ethnic background as risk factors, screening family members for PKD, pancreatic cysts, diverticulosis and diverticulitis in people with PKD, malabsorption problems, polycystic liver disease, hernia and polycystic kidney, neurologic involvement, cerebral aneurysms in people with PKD, cardiovascular problems associated with PKD, pregnancy, drug therapy, blood pressure considerations, kidney infections, the use of antibiotics, urinary tract infections, kidney stones, estrogen replacement therapy, renal function tests, dialysis therapy, peritoneal dialysis, vascular access, recurrence of PKD in a newly-transplanted kidney, the impact of immunosuppressive drugs on PKD, nutrition, protein intake, soy protein versus animal protein, flax seed, phosphorus, sodium restriction, vitamins, chemotherapy, exercise, medical nutrition therapy (MNT), the relationship between primary care physicians and nephrologists, medications that can be damaging to the kidneys, diagnostic tests used to monitor PKD, and pain management. The fact sheet includes many brief case-report type questions to help readers with specific issues.
Full Record Printer Friendly Version
Volume Progression in Polycystic Kidney Disease. New England Journal of Medicine. 354(20): 2122-2130. May 18, 2006.
This article considers the problem of volume progression in autosomal dominant polycystic kidney disease (ADPKD). ADPKD is characterized by progressive enlargement of cyst-filled kidneys. The authors report on a 3-year study in which they measured the rates of change in total kidney volume, total cyst volume, and iothalamate clearance in patients with ADPKD (n = 232, aged 15 to 46 years). Results showed that total kidney volume and total cyst volume increased exponentially, a result consistent with an expansion process dependent on growth. Total cyst volume increased by a mean of 203 milliliters-plus or minus 246 milliliters-over a 3-year period among 214 patients. The baseline total kidney volume predicted the subsequent rate of increase in volume, independent of age. A baseline total kidney volume above 1500 milliliters in 51 patients was associated with a declining glomerular filtration rate (GFR). Total kidney volume increased more in 135 patients with PKD1 mutations than in 28 patients with PKD2 mutations. The authors conclude that kidney enlargement resulting from the expansion of cysts in patients with AKPKD is continuous and quantifiable and is associated with the decline of renal function. 4 figures. 1 table. 29 references.
Full Record Printer Friendly Version
Eating Well for Two. PKD Progress. 21(1): 12-13, 24. Spring 2005.
This newsletter article discusses nutrition in pregnant women with polycystic kidney disease (PKD). The author contends that most women with PKD can have healthy, uncomplicated pregnancies, especially if they start out with a creatinine level less than 2 milligrams per deciliter and do not have hypertension (high blood pressure). Two potential, nutritionally-modifiable risk factors for pregnant women with PKD are hypertension and urinary tract infections. The article focuses on the role of nutrition in a healthy pregnancy in this patient population. Topics include increased protein needs during pregnancy, how to maintain a healthy sodium balance, calcium, cranberry juice, high fruit and vegetable intake, the use of iron supplements, omega-3 fatty acids, and the importance of not gaining weight during pregnancy. One sidebar refers readers to the Nutrient Analysis Database on the U.S. Department of Agriculture website (www.nal.usda.gov/fnic/foodcomp/search).
Full Record Printer Friendly Version
Evaluation and Preparation of Renal Transplant Candidates. IN: Danovitch, G.M. Handbook of Kidney Transplantation. Philadelphia, PA: Lippincott Williams and Wilkins. 2005. pp. 169-192.
The preparation of patients with end-stage renal disease for kidney transplantation should start from the time of recognition of progressive chronic kidney disease (CKD). This chapter on the evaluation and preparation of renal transplant candidates is from a handbook that offers a practical guide for health care providers who manage kidney transplant patients. The authors note that the management of these patients consists of an initial evaluation followed, if they are appropriate transplant candidates, by their supervision while awaiting transplantation. Initial evaluation is designed not only to assess the chances of recovery from surgery, but also to increase short- and long-term patient survival. The limited number of organs available has changed the focus of the transplant evaluation toward better long-term outcome over short-term benefits. The authors first focus on the initial recipient evaluation and then consider the management of the waiting list for deceased donor transplantation. Specific topics covered include the benefits of early referral, patient education, the routine evaluation, the evaluation of specific transplant risk factors related to organ system disease (cardiovascular disease, cerebrovascular and peripheral vascular disease, malignancy, infections, gastrointestinal disease, pulmonary disease, urologic evaluation, renal osteodystrophy and metabolic bone disease, and hypercoagulable states), and risk factors related to specific patient characteristics (aged, obesity, highly sensitized patients, previously transplanted patients, and candidates for double-organ transplants). An additional section considers the relevance of the etiology of renal disease to the transplant evaluation, including diabetes mellitus, focal and segmental glomerulosclerosis, recurrent glomerulonephritis, thrombotic thrombocytopenic purpura, systemic lupus erythematosus and vasculitis, oxalosis and oxaluria, Fabry disease, Alport syndrome, sickle cell disease, amyloidosis and plasma cell dyscrasias, and polycystic kidney disease. 1 figure. 5 tables. 16 references.
Full Record Printer Friendly Version
Facts About Kidney Disease. Rockville, MD: American Kidney Fund. 2005. 8 p.
This brochure provides basic information about kidney disease. Topics include the anatomy and physiology of kidneys, common kidney diseases, risks for kidney disease, the symptoms of kidney disease, diagnostic tests used to confirm kidney disease, treatments for kidney failure, and prevention of kidney disease. Kidney diseases discussed include chronic kidney disease (CKD), which can occur from many different causes, kidney stones, polycystic kidney disease (PKD), kidney infections (pyelonephritis), simple kidney cysts, kidney cancer, and the nephritic syndrome. Diagnostic tests described include glomerular filtration rate (GFR), urine tests, blood pressure monitoring, blood glucose testing, kidney biopsy, and imaging tests (CT, MRI). Treatment options include hemodialysis, peritoneal dialysis, and kidney transplantation. Readers are encouraged to contact the American Kidney Fund (AKF) HelpLine (800–638–8299 or HelpLine@kidneyfund.org). The brochure is illustrated with black-and-white photographs. 5 figures.
Full Record Printer Friendly Version
Getting Back on the Wagon and Getting Rid of the Saddle. PKD Progress. 18(1): 8-9. Spring 2005.
This article, from a journal for people with polycystic kidney disease (PKD), emphasizes the importance of weight management as part of a complete program of disease management. The author cautions that excess body weight can increase blood pressure and may lead to hormonal changes (hyperinsulinemia) that could accelerate the progression of PKD. The author then outlines recommendations for healthy weight loss, including working out with friends, reducing the amount of fat in one's diet, eating smaller portions, avoiding high-calorie snack foods, increasing fiber in one's diet, meal planning, packing healthy food, avoiding liquid calories (sodas, alcohol), and exercising. The author concludes by reminding readers that these healthy approaches are useful not only for weight loss but also for general health and well-being.
Full Record Printer Friendly Version
How to Pick a Good Nephrologist. PKD Progress. 20(1): 11-13. Spring 2005.
This article, from a journal for people with polycystic kidney disease (PKD), outlines suggestions to help readers choose a good nephrologist (kidney specialist). The author stresses that selecting a physician who meets one's needs is a multi-step process that includes networking, talking to one's primary care physician, consulting academic resources, and considering issues of insurance. The author also notes that reasonable access to the physician is also important; no matter how good the physician, if the practice is not well-managed, that physician may not be the best choice. A final section discusses advocacy and learning to be one's own health care advocate. One sidebar lists some online resources for finding and learning about doctors and hospitals.
Full Record Printer Friendly Version
Mechanistic Approach to Inherited Polycystic Kidney Disease. Pediatric Nephrology. 20(5): 558-566. May 2005.
This article discusses the use of a mechanistic approach to the pathogenesis of inherited polycystic kidney disease. The authors note that although some of these inherited cystic diseases are rarely encountered, the number of affected people (approximately 6.5 million worldwide) justifies the investigations into their pathogenesis. The authors discuss the disease burden worldwide, the genetics of the autosomal dominant diseases, medullary cystic kidney disease, autosomal dominant polycystic kidney disease (ADPKD), tuberous sclerosis complex, autosomal recessive polycystic kidney disease (ARPKD), nephronophthisis, Bardet-Biedl syndrome, the dysregulation of renal tubular epithelial cell biology, the pathogenesis of cysts, tubules, and cilium. 5 figures. 1 table. 55 references.
Full Record Printer Friendly Version
Medical and Surgical Aspects of Kidney Donation. IN: Danovitch, G.M. Handbook of Kidney Transplantation. Philadelphia, PA: Lippincott Williams and Wilkins. 2005. pp. 135-168.
The appropriate identification and preparation of kidney donors (both living and deceased) contribute critically to the success of the transplant endeavor on both the individual and the national levels. This chapter on the medical and surgical aspects of kidney donation is from a handbook that offers a practical guide for health care providers who manage kidney transplant patients. The authors divide the chapter into two sections: Part I addresses the selection and evaluation of living donors and the surgical techniques of living donor nephrectomy; Part II discusses these same issues for deceased kidney donors. Specific topics include the role of informed consent, the evaluation process, the psychosocial evaluation, risks of donation, donor age, assessment of surgical risks, the risk of disease transmission to the recipient, evaluation of future risk to the donor, assessment of renal function (glomerular filtration rate, proteinuria, hematuria, hypertension, diabetes, obesity, nephrolithiasis, inherited renal disease, autosomal dominant polycystic kidney disease, Alport syndrome, familial primary glomerulonephritis, and systemic lupus erythematosus), surgical evaluation of the living kidney donor, surgical techniques for living donor nephrectomy, long-term postnephrectomy issues (renal function, pregnancy, employment and insurance, and long-term medical care), and controversies and innovations in living kidney donor practice, including biologically unrelated donors, incompatible donor and recipient, paid donation, and the living donor registry. The second section discusses contraindications to deceased donor donation, the role of donor age, expanded criteria donors, donor biopsy, nephron dose, donation after cardiac death, diagnosis of brain death, techniques of deceased donor organ retrieval, and deceased donor kidney preservation. 2 figures. 10 tables. 32 references.
Full Record Printer Friendly Version
PKD: A Progress Report, New Directions in Research. Nephrology News & Issues. 19(12): 39-40. November 2005.
Polycystic kidney disease (PKD) causes end-stage renal disease (ESRD) in 50 percent of affected individuals. This article brings readers up-to-date about research activities into understanding the molecular basis of PKD. The author discusses advances in gene identification, including mapping, cloning, and sequencing; analysis of the genes and encoded proteins; the mechanisms of disease progression; renal functional deterioration; and advances that can contribute to clinical therapies. The author notes that PKD is typically such a slowly progressive disease that it is hard to evaluate potential therapies. The development of surrogate markers for disease progression may address this concern. The author briefly reports on the CRISP study that evaluated renal anatomic changes, measured by periodic magnetic resonance imaging (MRI), in patients with PKD.
Full Record Printer Friendly Version
Polycystic Kidney Disease (PKD). American Family Physician. 71(1): 135-136. January 1, 2005.
This patient education fact sheet reviews the problem of polycystic kidney disease (PKD), a condition in which sacs of fluid grow in the kidneys. If too many cysts grow or if they become too big, the kidneys are damaged. The cysts may also be painful or get infected. The fact sheet reviews the symptoms of PKD, the impact of PKD on lifestyle and lifespan, diagnostic tests that may be used to confirm the presence of PKD, who should be tested for PKD, and the diagnosis of PKD in unborn babies. PKD tends to run in families and children of people with PKD have a 50 percent chance of getting the disease. Blank space for notes is also included.
Full Record Printer Friendly Version
Pregnancy and PKD. PKD Progress. 21(1): 6-7. Spring 2005.
This newsletter article discusses pregnancy in women with polycystic kidney disease (PKD). The author discusses medications, supplements, the problems of pre-eclampsia and hypertension, decreased kidney function, and other women's health issues. The brochure Health Tips for Living with Polycystic Kidney Disease by Dr. Arlene Chapman is used as a basis for much of the discussion. Many women with PKD can experience a positive and successful pregnancy, but a woman with PKD must be careful to protect her own health and that of her baby. For women with pre-existing hypertension, careful, frequent evaluation of blood pressure during the second and third trimesters is crucial. The author cautions that women with established renal insufficiency have less than a 50 percent chance of having a baby that survives pregnancy. One sidebar offers a brief PKD pregnancy checklist of health issues for women to discuss with their health care providers.
Full Record Printer Friendly Version
Understanding Conditions That Lead to Chronic Kidney Disease. Kidney Beginnings. 4(4): 6-7, 22. Special Edition 2005.
This article familiarizes readers with some of the conditions and diseases that can eventually lead to chronic kidney disease (CKD). The author focuses primarily on diabetes mellitus and hypertension (high blood pressure). Of all the patients who experience kidney failure, 43.5 percent have diabetes and 26.5 percent have high blood pressure. High blood glucose levels associated with diabetes can disrupt the structure and function of blood vessels, including those that are involved in the filtration system of the kidneys. Damaged kidneys do not do a good job of cleaning out the body’s waste and extra fluids. Readers are advised to keep their blood glucose and blood pressure levels as close to normal as possible. Other conditions briefly discussed are glomerulonephritis, nephrotic syndrome, and polycystic kidney disease (PKD). Readers are referred to a booklet available from the American Association of Kidney Patients (AAKP) for more information (800-749-2257).
Full Record Printer Friendly Version
About Chronic Kidney Disease. El Segundo, CA: DaVita Inc. 2004. 4 p.
Healthy kidneys function to remove extra water and wastes from the body, to help control blood pressure, to keep body chemicals in balance, to keep bones strong, to tell the body to make red blood cells, and to help children grow normally. This patient education fact sheet offers a basic description of chronic kidney disease (CKD), a condition that occurs when the kidneys are no longer able to clean toxins and waste products from the blood or perform their functions to full capacity. Written in a question-and-answer format, the fact sheet discusses acute renal failure and how it differs from CKD, the main causes of kidney disease, diabetes-related kidney disease, kidney stones, parathyroid hormone (PTH) and calcium, polycystic kidney disease (PKD), the symptoms of CKD, and diagnostic tests used to confirm CKD. The fact sheet concludes with information about a patient education program sponsored by DaVita (the producer of the fact sheet and a provider of in-center hemodialysis nationally).
Full Record Printer Friendly Version
Polycystic Kidney Disease. New England Journal of Medicine. 350(2): 151-164. January 2004.
This article reviews the mechanisms of polycystic kidney disease (PKD), a leading cause of end-stage renal failure and a common indication for dialysis or renal transplantation. The age at onset, the severity of symptoms, and the rates of progression to end-stage renal disease (ESRD) or death vary widely in this group of diseases. Topics covered include autosomal dominant PKD, autosomal recessive PKD, familial nephronophthisis, medullary cystic kidney disease, cell biology, molecular biology, developmental regulation and programming, and prospects for prognosis and therapy. 5 figures. 2 tables. 98 references.
Full Record Printer Friendly Version
Solving the Protein Puzzle for Those Who Are Early-Stage PKD and Not on Dialysis. PKD Progress. 19(1): 10-11. Spring 2004.
Protein is an essential nutrient that is a chief component of cells in the body. Protein is essential for building and repairing body tissues, supporting the immune system, and providing the proper balance of neurotransmitters. For people with polycystic kidney disease (PKD), protein needs vary according to their kidney function. This article considers the protein needs of people with early stage PKD who are not yet on dialysis. Topics include the foods that contain protein, guidelines for amounts of protein to be eaten, the different types of protein (animal versus vegetable), and the use of soy proteins. One chart lists common protein sources (animal and vegetable), and the grams of protein in one serving size (also described). 1 table.
Full Record Printer Friendly Version
Displaying all search results.
Start a new search.
|
