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Your search term(s) "irritable bowel syndrome" returned 145 results.
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Appendix A: The Rome III Diagnostic Criteria for the Functional Gastrointestinal Disorders. IN: Drossman, D., ed. Understanding the Irritable Gut: The Functional Gastrointestinal Disorders. McLean, VA: Degnon Associates, Inc. 2008. pp 183-199.
This appendix is from a book that helps doctors and patients better understand functional gastrointestinal disorders (FGIDs), with text based on information developed by the Rome Foundation to identify, classify, and treat these disorders. This appendix presents the Rome criteria for the diagnoses of FGIDs; the criteria were developed by teams of experts to define patients for scientific study and help practicing doctors more precisely identify the disorders. The disorders covered include functional heartburn, functional chest pain of presumed esophageal origin, functional dysphagia, globus, functional dyspepsia, postprandial distress syndrome, epigastric pain syndrome, belching disorders, chronic idiopathic nausea, functional vomiting disorders, cyclic vomiting syndrome (CVS), rumination syndrome in adults, irritable bowel syndrome, functional bloating, functional constipation, functional diarrhea, functional abdominal pain syndrome (FAPS), functional gallbladder and Sphincter of Oddi disorders, functional fecal incontinence, functional anorectal pain, and functional defecation disorders. The diagnostic criteria for both childhood and adult FGIDs are included, although the remainder of the appendix only focuses on adult disorders. Readers are cautioned that the criteria are not meant for self-diagnosis and that a confident diagnosis can only be safely arrived at after a careful history and physical examination by a doctor. The diagnostic criteria are scheduled to be updated again in 2012.
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Colon: Questions and Answers. IN: Hauser, S., ed. Mayo Clinic Gastroenterology and Hepatology Board Review. 3rd ed. New York, NY: Informa Healthcare USA. 2008. pp 271-280.
This section of questions and answers is from a comprehensive textbook that provides an in-depth examination of essential knowledge in gastroenterology, hepatology, and the related areas of pathology, endoscopy, nutrition, and radiology. This section helps readers review seven chapters on the colon, including clinical aspects, therapy, extraintestinal manifestations and cancer, gastrointestinal infections, diverticular disease, colorectal neoplasms, irritable bowel syndrome (IBS), constipation, and disorders of the pelvic floor function. The section consists of 21 multiple choice questions, followed by annotated answers that explain each of the correct choices.
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Evaluation of Lower Functional Gut Disorders. Canadian Journal of Gastroenterology. 22(7): 614-616. July 2008.
This article reviews the current thinking regarding the endoscopic evaluation of lower functional gut disorders, including irritable bowel syndrome (IBS). The authors note that the key to diagnosing functional disorders is knowing how much investigation is needed before making the diagnosis. They review recommended patient approaches for IBS, for alternating or mixed bowel pattern IBS, for diarrhea-predominant IBS, and for constipation-predominant IBS. One section briefly considers some additional testing that might be indicated, including that for lactose intolerance or small intestinal bacterial overgrowth (SIBO). The author concludes that although the diagnostic accuracy of IBS is excellent, shifts in IBS symptomatology are common. Typical symptoms without alarm features generally do not require exhaustive evaluation before the initiation of therapy. In patients with alarm features or diarrhea-predominant symptoms, or in patients who fail initial supportive management, further directed investigations may be warranted. 24 references.
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Functional Gastrointestinal Disorders and the Potential Role of Eosinophils. Gastroenterology Clinics of North America. 37(2): 383-396. June 2008.
This article about functional gastrointestinal disorders and the potential role of eosinophils is from an issue of Gastroenterology Clinics of North America that focuses on eosinophilic and autoimmune gastrointestinal disease. Eosinophils are a type of white blood cell. The authors review the Rome III classification of the functional gastrointestinal disorders (FGIDs), noting that abdominal pain, disordered defecation, and meal-related discomfort are common symptoms for a range of FGIDs. The current model of disease for FGIDs reflects an interaction between psychosocial factors, including stress and anxiety, gut physiology, and the brain-gut axis, which results in visceral hypersensitivity or dysmotility. The article covers eosinophils in the gastrointestinal tract, the normal eosinophil count in the gut, allergy and atopy in FGIDs, infection and gastrointestinal disorders, eosinophils in the duodenum in functional dyspepsia and irritable bowel syndrome (IBS), eosinophil function in the gut, eosinophil interactions in gut mucosa, and eosinophils in gastrointestinal disease. The authors propose that neural-mast cell-eosinophil interaction may cause abdominal pain or meal-related symptoms characteristic of functional disease. The trigger may be a pathogen, food, infection, or other allergen in the gut mucosa. 3 figures. 82 references.
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2007 Symposium Summary Report. Digestive Health Matters. 16(4): 4-7. Winter 2007.
This article summarizes the presentations and findings of the 7th International Symposium on Functional Gastrointestinal Disorders that was held in Milwaukee, WI, in April 2007. The introductory comments focus on recent changes in the understanding and acceptance of functional gastrointestinal (GI) disorders, on cutbacks in federal budget support for health sciences research, and the work of the Functional Brain Gut Group (FBG). Other topics covered in the summary include changes in the basic understanding of illness and disease; definitions of functional GI disorders and motility; the biopsychosocial model; the role of genetic influences; the pathophysiology of gut dysfunction; the role of serotonin, mast cells, bacteria, stress, and brain-gut interactions; postinfectious irritable bowel syndrome (IBS); diagnoses based on symptom clusters; and the role of biomarkers. A final section reports on some future directions anticipated in this area of research. Readers are referred to the International Foundation for Functional Gastrointestinal Disorders (IFFGD) webpage (www.iffgd.org/site/learning-center/video-corner) for more information about new developments regarding research, diagnosis, and treatment of functional GI and motility disorders.
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Functional Gastrointestinal Disorders: Nature and Diagnosis. IN: Drossman, D., ed. Understanding the Irritable Gut: The Functional Gastrointestinal Disorders. McLean, VA: Degnon Associates, Inc. 2008. pp 33-94.
This section of six chapters is from a book that helps doctors and patients better understand functional gastrointestinal disorders (FGIDs), with text based on information developed by the Rome Foundation to identify, classify, and treat these disorders. This section begins with Chapter 5, which outlines the diagnostic strategies and classification for FGIDs. Chapter 6 focuses on irritable bowel syndrome (IBS), the most studied FGID and the one that has validated diagnostic criteria. Chapter 7 covers functional constipation, which must be differentiated from organic disorders, some of which are themselves uncommon and poorly understood. Chapter 8 discusses functional diarrhea, not because it is common, but rather because it may be diagnosed only after meticulous testing for known causes of chronic diarrhea. Chapter 9 covers functional dyspepsia, a condition that is difficult to define and was often called nonulcer dyspepsia. The Rome process has made the diagnosis more inclusive and has altered the classification, subtypes, and criteria of functional dyspepsia. Chapter 10 describes the functional esophageal disorders, which are among the few FGIDs that are best diagnosed by exclusion. Chapter 11 reviews the functional anorectal disorders and Chapter 12 covers the remaining disorders not discussed previously. Each chapter includes black-and-white and color illustrations and concludes with a brief list of recommended sources for more information.
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Functional Gut Disorders and Inflammatory Bowel Disease: Comorbidity and Clinical Challenges. Practical Gastroenterology. 32(10): 10-17. October 2008.
This review article considers the comorbidity and clinical challenges of managing patients with both functional gut disorders and inflammatory bowel disease. The authors stress that inflammation has a profound impact on the gastrointestinal nervous system, during an inflammatory insult and in periods of remission, and at the site of inflammation and at a distance from this site. The importance of this interaction is illustrated by the higher prevalence of functional gut disorders (FGD) in patients with inflammatory bowel disease (IBD). The review finds that abnormalities of gastrointestinal sensory and motor function such as the irritable bowel syndrome (IBS) occur more frequently in patients with IBD, during inflammatory episodes and in periods of remission, and have a major impact on their quality of life. Motility and sensitivity disturbances often persist after an inflammatory episode, resulting in motility and sensitivity symptoms even during remission of the IBD. The authors conclude that the clinical manifestations of these motility and sensitivity disorders vary and are often difficult to treat, mainly because therapeutic guidelines and specific diagnostic tests to distinguish IBD in remission from FGD are lacking. 71 references.
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How Man’s Commonest Infection Kept its Secret: The H. Pylori Story - Any Lessons for the Functional Gastrointestinal Disorders?. Digestive Health Matters. 17(3): 3-4. Fall 2008.
This article reminds readers of the role of the Helicobacter pylori bacterium in the development of most peptic ulcers in the stomach and duodenum. The author describes the delay in the identification and understanding of the role this bacterium plays in the development of ulcers, discussing the gastric acid theory, research studies that sought to find the causes of ulcers, and the 10-year lag between the report of H. pylori’s role and the medical community’s acceptance of this information. The author considers the present theories being explored to find the cause of the functional gastrointestinal disorders, including irritable bowel syndrome (IBS), visceral hypersensitivity, psychological factors, infection, and the brain-gut connection. A final section encourages health care providers, researchers, and patients to remain open-minded in the search for better understanding of the functional gastrointestinal disorders (FGID).
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Irritable Bowel Syndrome (IBS) in Children. Bethesda, MD: National Digestive Diseases Information Clearinghouse. 2008. 6 p.
This fact sheet describes irritable bowel syndrome (IBS) in children. IBS is a functional gastrointestinal disorder marked by abdominal pain or discomfort, bloating, and irregular bowel habits, such as diarrhea or constipation. Functional gastrointestinal disorders are defined by their symptoms. IBS can cause a great deal of discomfort and distress, but it is not life threatening, does not damage the bowel, and does not progress to other diseases. The fact sheet answers common questions about IBS in children, including the anatomy and function of the bowel, the causes of IBS, who gets IBS, the symptoms, diagnostic strategies, treatment options, and the outlook for a child with IBS. Treatment for IBS includes dietary changes, medication, and stress management. The fact sheet includes a brief description of current research in this area. Readers are referred to two resource organizations: the International Foundation for Functional Gastrointestinal Disorders at 1–888–964–2001 or www.iffgd.org and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition at 215–233–0808 or www.naspghan.org. The document concludes with a summary of the activities of the National Digestive Diseases Information Clearinghouse (NDDIC), a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). 1 figure.
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Irritable Bowel Syndrome (IBS), Heartburn, Dyspepsia: What’s the Difference? Digestive Health Matters. 17(1): 8-11. Spring 2008.
This article helps readers understand the differences among irritable bowel syndrome (IBS), heartburn, and dyspepsia. IBS is characterized by discomfort or pain anywhere in the abdomen that is relieved by having a bowel movement or that occurs with a change to looser or firmer stools. Dyspepsia is characterized by discomfort or pain, but only in the upper abdomen. Dyspepsia is sometimes associated with eating, but not with having a bowel movement. Heartburn is characterized by discomfort or pain, often described as burning pain in the lower chest behind the breastbone. Heartburn typically occurs after certain meals or when bending over or lying down. The author notes that the symptoms of each of these functional gastrointestinal (GI) disorders can be chronic, often beginning in youth and occurring periodically over a person’s lifetime. Because the management approach to each of these disorders is different, accurate diagnosis is important before undergoing a treatment plan. The article includes one table of warning symptoms, that is, those problems that require immediate medical attention. The author concludes that the distinction of these three disorders from one another depends on the location of the pain or discomfort, the presence or absence of a relationship to having a bowel movement, and the response to acid-suppressing drugs. 1 figure. 3 tables. 2 references.
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